About Xeomin®
Xeomin® is unique. It was the first clinically proven anti-wrinkle injection uniquely purified to remove proteins unnecessary for treatment.
Xeomin® is indicated for temporary improvement in the appearance of moderate to severe glabellar lines in adult patients. Xeomin® can help differentiate your practice.
Xeomin® is different in ways that matter to you and to your patients.
*Studies have not been performed to determine whether the presence or absence of complexing/unnecessary proteins has a long-term effect on safety or efficacy.
Mechanism of Action
- Xeomin® is a Botulinum Toxin Type A that blocks transmission of acetylcholine (ACh) from neuron to muscle
- This inhibits muscle contraction and causes muscle paresis (weakness) or paralysis
- Botulinum Toxin Type A only affects "cholinergic neurons" (neurons which use acetylcholine as a neurotransmitter)
- Botulinum Toxin Type A effects dissipate after ~ 3 months because new SNAP-25 proteins take 3 months to be synthesized
Before & After

*Individual Results May Vary*
Frequently Asked Questions
The dosage of units and reconstitution is the same for both. Hence, for the treatment of glabella lines, the minimum indicated number of units is 20 units. As with any product, some patient variability exists and some patients may require higher dosage.
Xeomin ® can be injected in the same areas just like Botox® and Dysport®. Some of these areas are FDA approved while others are not. That’s why it’s important to trust an expert when it comes to facial injections like Dr.Avaliani.
Common areas of treatments include:
- Horizontal lines on forehead
- Lines between eyebrows aka 11 lines (Glabella)
- Lines around eyes (Lateral Canthal lines)
- Bunny lines (wrinkles on your nose)
- Smoker’s lines- vertical lines on the upper lip
- Wide jaw-slimming down the jaw line
- Neck bands- Platysma neck cords
- Hyperhidrosis – excessive sweating
- Gummy smile
- Migraine headache
- Chin wrinkles
- Liquid eye lift
- Brow lift
There are no FDA approved studies for Xeomin injection for adults less that 18 years of age. During the clinical trials the maximum age of the patients was 65 years old.
Adults from 18 to 65 and older are all candidates for the treatment. There is no right age to start treatment, but Xeomin, Botox and Dysport are all being recognized as a preventative measurement to starting injections early to avoid the lines from getting deeper and becoming more prominent.
If you have pre-existing neuromuscular disorders such as (Myasthenia gravis, Lambert-Eaton Syndrome, amyotrophic lateral sclerosis (ALS) should not be injected. If you also have pre existing swallowing or breathing problems, you should be advised against Xeomin treatment. Patients with evidence of active infection or inflammation at the site of potential treatment area, should not be injected until inflammation or infection completely resolves. Dr. Avaliani will perform a detailed history intake and physical exam to determine if Xeomin is the right treatment for you.
The best answer to these questions is: If you are bothered by the wrinkle lines on your face and want them removed, then you should schedule a consultation with Dr. Avaliani to determine if Xeomin will work for you.